Myocardial reperfusion reverses the J-curve association of cardiovascular risk and diastolic blood pressure in patients with left ventricular dysfunction and heart failure after myocardial infarction: insights from the EPHESUS trial.

Date publication

mars 2020

Journal

European heart journal

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick

Tous les auteurs :
Böhm M, Ferreira JP, Mahfoud F, Duarte K, Pitt B, Zannad F, Rossignol P

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32118256

Résumé

The described association of low diastolic blood pressure (DBP) with increased cardiovascular outcomes could be due to reduced coronary perfusion or is simply due to reverse causation. If DBP is physiologically relevant, coronary reperfusion after myocardial infarction (MI) might influence DBP-risk association.

Mots clés

J-curve, Acute myocardial infarction, Blood pressure risk association, Coronary perfusion, Diastolic blood pressure, Heart failure, Systolic blood pressure

Référence

Eur. Heart J.. 2020 Mar 2;: