Vibration of effects from diverse inclusion/exclusion criteria and analytical choices: 9216 different ways to perform an indirect comparison meta-analysis.

Fiche publication

Date publication

septembre 2019

Journal

BMC medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Dr HAMMAS Karima

Tous les auteurs :
Palpacuer C, Hammas K, Duprez R, Laviolle B, Ioannidis JPA, Naudet F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/31526369

Résumé

Different methodological choices such as inclusion/exclusion criteria and analytical models can yield different results and inferences when meta-analyses are performed. We explored the range of such differences, using several methodological choices for indirect comparison meta-analyses to compare nalmefene and naltrexone in the reduction of alcohol consumption as a case study.