Fiche publication
Date publication
avril 2020
Journal
Molecular nutrition & food research
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DELMAS Dominique
,
Pr GHIRINGHELLI François
,
Pr SCHINI-KERTH Valérie
,
Dr AUGER Cyril
,
Dr CHALMIN Fanny
,
Dr AIRES Virginie
,
Dr LIMAGNE Emeric
Tous les auteurs :
Chalons P, Courtaut F, Limagne E, Chalmin F, Cantos-Villar E, Richard T, Auger C, Chabert P, Schini-Kerth V, Ghiringhelli F, Aires V, Delmas D
Lien Pubmed
Résumé
It is well established that immune response and inflammation promote tumoral progression. Immune cells communicate through direct contact or through cytokine secretion, and it is the expression of these mediators and of the pro-inflammatory status that will tip the balance toward tumor progression or anti-tumor immunity. We have demonstrated that a red wine extract (RWE) was able to decrease inflammation through its action on the inflammasome complex. In this study, we sought to determine whether an RWE could impact other key actors of inflammation, in particular T helper 17 (Th17) immune cells.
Mots clés
Interleukins, Polyphenols, Red wine extract, Th17 lymphocytes
Référence
Mol Nutr Food Res. 2020 Apr 18;:e1901286
