Two Diagnostic Criteria of Optical Spectroscopy for Bladder Tumor Detection: Clinical Study using 5-ALA induced fluorescence and Mathematical Modeling.

Date publication

mai 2020

Journal

Photodiagnosis and photodynamic therapy

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BLONDEL Walter , Pr DAUL Christian , Dr AMOUROUX Marine

Tous les auteurs :
Kalyagina N, Loshchenov M, Amouroux M, Daul C, Kudashev B, Blondel W, Loschenov V

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32445963

Résumé

The study proposes to improve bladder cancer diagnosis by (i) photodynamic diagnosis (PDD) using red-light excitation (632.8 nm) of 5-ALA induced-protoporphyrin IX in 9 patients' bladder associated to the analysis of two types of signals to improve the diagnostic accuracy, and (ii) numerical modeling of scattering coefficient for providing biological explanations of the results obtained.

Mots clés

bladder cancer, diffuse reflectance, fluorescence, laser signal, optical spectroscopy, photodynamic diagnosis, scattering

Référence

Photodiagnosis Photodyn Ther. 2020 May 20;:101829