Applications of Elastography in Ablation Therapies: An Animal Model Study.

Fiche publication

Date publication

juillet 2020

Journal

Journal of laparoendoscopic & advanced surgical techniques. Part A

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MARESCAUX Jacques

Tous les auteurs :
Giménez ME, Davrieux CF, Saccomandi P, Serra E, Quero G, Palermo M, Marescaux J

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32668183

Résumé

Ablation therapies are one of the main local treatments for solid organ tumors. After applying any ablation therapy, few days should be waited to perform an imaging study and analyze the result. In this work, we analyzed the correlation between elastography monitoring after procedure and the result of ablation. The objective of this study is to determine tissue changes in short term after the application of ablation systems using different diagnostic imaging methods. Descriptive study in an swine model. Different types of ablation therapies (radiofrequency ablation, microwave ablation [MWA], and LASER ablation [LA]) were applied in the liver and kidneys. We compared their results by medical image monitoring (ultrasound, computed tomography, elastography) and macroscopic analysis. All the animals survived the procedures. No major intraoperative complications were reported. We determined the characteristics of each procedure. MWA session was faster than the other types of ablation therapies. Regarding ablation area diameters, the largest was achieved with MWA and the smallest with LA. Macroscopically, we observed a central ablation zone, a peripheral ablation zone, and surrounding normal tissue. It was correlated with elastography images. Monitoring of the results of ablation therapies shortly after their application is possible through imaging studies. It allows determining the size of the ablation zone, its characteristics, ruling out complications, and its early results. Elastography could efficiently support this goal.