Fiche publication


Date publication

juillet 2020

Journal

International urology and nephrology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick


Tous les auteurs :
Copur S, Sag AA, Afsar B, Rossignol P, Covic A, Kanbay M

Résumé

Chronic kidney disease is prevalent, affecting more than one in ten adults. In this population, metabolic acidosis is considered a key underlying pathophysiological feature, tying together bone mineral disorders, sarcopenia, insulin resistance, vascular calcification, pro-inflammatory and pro-thrombotic states. This review aims to address the paucity of literature on alkalinizing agents, a promising treatment option that has known adverse effects.

Mots clés

Alkaline treatment, Bicarbonate, Chronic kidney disease, End-stage renal disease, Metabolic acidosis

Référence

Int Urol Nephrol. 2020 Jul 13;: