Identification of an oral microbiota signature associated with an impaired orosensory perception of lipids in insulin-resistant patients.

Date publication

juillet 2020

Journal

Acta diabetologica

Auteurs

Membres identifiés du Cancéropôle Est :
Pr VERGES Bruno

Tous les auteurs :
Besnard P, Christensen JE, Bernard A, Simoneau-Robin I, Collet X, Verges B, Burcelin R

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32676702

Résumé

Type 2 diabetes leads to multiple sensory dysfunctions affecting notably the gustatory sensitivity. Although this sensory defect, by impacting food choices, might lead to unhealthy eating behavior, underlying mechanisms remains poorly studied. We have recently reported that the composition of microbiota in contact with circumvallate gustatory papillae might affect the orosensory perception of lipids in lean and normoglycemic obese subjects. This finding has prompted us to explore whether such a phenomenon also occurs in diabetic obese patients.

Mots clés

Circumvallate papillae, Lipids, Microbiota, Taste sensitivity, Type 2 diabetes

Référence

Acta Diabetol. 2020 Jul 16;: