Fiche publication
Date publication
juillet 2020
Journal
Clinics and research in hepatology and gastroenterology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BAUMERT Thomas
,
Dr HABERSETZER François
,
Pr PESSAUX Patrick
Tous les auteurs :
Tripon S, Mayer P, Svab A, Habersetzer F, Pessaux P, Baumert TF, Enescu I
Lien Pubmed
Résumé
Cirrhotic patients may present loculated ascites. We report a case of a 49-years old patient with cirrhosis and loculated infected ascites. Conventional and ultrasound (US)-guided paracentesis were ineffective. Moreover, US-guided drainages with 10 F drains could drain only small quantities of ascites localized in the largest loculated areas. Despite an adapted and long antibiotic therapy, the infection persisted. Intraabdominal fibrinolysis allowed the destruction of the fibrin septa, a better drainage and the sterilization of the ascites fluid. This is the first case report of effective intraabdominal fibrinolysis with urokinase in difficult to treat loculated infected ascites.
Mots clés
Cirrhosis, Fibrinolysis, Loculated ascites
Référence
Clin Res Hepatol Gastroenterol. 2020 Jul 9;:
