Multi-proteomic approach to predict specific cardiovascular events in patients with diabetes and myocardial infarction: findings from the EXAMINE trial.

Fiche publication

Date publication

août 2020

Journal

Clinical research in cardiology : official journal of the German Cardiac Society

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick

Tous les auteurs :
Ferreira JP, Sharma A, Mehta C, Bakris G, Rossignol P, White WB, Zannad F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32789678

Résumé

Patients with diabetes who had a recent myocardial infarction (MI) are at high risk of cardiovascular events. Therefore, risk assessment is important for treatment and shared decisions. We used data from EXAMINE trial to investigate whether a multi-proteomic approach would provide specific proteomic signatures and also improve the prognostic capacity for determining the risk of cardiovascular death, MI, stroke, heart failure [HF], all-cause death, and combinations of these outcomes.