Fiche publication
Date publication
janvier 2020
Journal
Frontiers in microbiology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr VAN DORSSELAER Alain
,
Dr CARAPITO Christine
,
Dr HEINTZ Dimitri
,
Mme KOECHLER Sandrine
,
Mme COGNAT Valérie
Tous les auteurs :
Thompson D, Cognat V, Goodfellow M, Koechler S, Heintz D, Carapito C, Van Dorsselaer A, Mahmoud H, Sangal V, Ismail W
Lien Pubmed
Résumé
strain IGTS8 is the most extensively studied model bacterium for biodesulfurization of fossil fuels via the non-destructive sulfur-specific 4S pathway. This strain was initially assigned to and later to thus making its taxonomic status debatable and reflecting the limited resolution of methods available at the time. In this study, phylogenomic analyses of the whole genome sequences of strain IGTS8 and closely related rhodococci showed that and are very closely related species, that strain IGTS8 is a strain and that several strains identified as should be re-classified as . The genomes of strains assigned to these species contain potentially novel biosynthetic gene clusters showing that members of these taxa should be given greater importance in the search for new antimicrobials and other industrially important biomolecules. The plasmid-borne operon encoding fossil fuel desulfurization enzymes was present in IGTS8 and XP suggesting that it might be transferable between members of these species.
Mots clés
4S pathway, Rhodococcus, average nucleotide identity, biodesulfurization, dibenzothiophene, digital DNA-DNA hybridization, phylogenomics
Référence
Front Microbiol. 2020 ;11:1417
