Fiche publication
Date publication
août 2020
Journal
Organic letters
Auteurs
Membres identifiés du Cancéropôle Est :
Dr VALVERDE Ibai
Tous les auteurs :
Dejouy G, Renault K, Bonnin Q, Chevalier A, Michaudet C, Picquet M, Valverde IE, Romieu A
Lien Pubmed
Résumé
A simple and effective biocompatible domino reaction triggered by a model protease and leading to the formation of strongly fluorescent quinoxalin-2(1)-one -heterocycles is described. Some positive attributes including versatility and the ability to provide outstanding fluorescence "OFF-ON" responses were revealed by this work. They open the way for practical applications of this novel type of "covalent-assembly"-based fluorescent probe in the fields of sensing and bioimaging.
Référence
Org. Lett.. 2020 Aug 21;22(16):6494-6499
