Fiche publication


Date publication

janvier 2020

Journal

Therapeutic advances in medical oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SOCKALINGUM Ganesh


Tous les auteurs :
Medipally DKR, Cullen D, Untereiner V, Sockalingum GD, Maguire A, Nguyen TNQ, Bryant J, Noone E, Bradshaw S, Finn M, Dunne M, Shannon AM, Armstrong J, Meade AD, Lyng FM

Résumé

Screening for prostate cancer with prostate specific antigen and digital rectal examination allows early diagnosis of prostate malignancy but has been associated with poor sensitivity and specificity. There is also a considerable risk of over-diagnosis and over-treatment, which highlights the need for better tools for diagnosis of prostate cancer. This study investigates the potential of high throughput Raman and Fourier Transform Infrared (FTIR) spectroscopy of liquid biopsies for rapid and accurate diagnosis of prostate cancer.

Mots clés

FTIR spectroscopy, Raman spectroscopy, liquid biopsy, partial least squares discriminant analysis and classical least squares fitting analysis, principal component analysis, prostate cancer

Référence

Ther Adv Med Oncol. 2020 ;12:1758835920918499