A multidisciplinary weight loss intervention in obese adolescents with and without sleep-disordered breathing improves cardiometabolic health, whether SDB was normalized or not.

Date publication

juin 2020

Journal

Sleep medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MOUGIN-GUILLAUME Fabienne

Tous les auteurs :
Roche J, Corgosinho FC, Isacco L, Scheuermaier K, Pereira B, Gillet V, Moreira GA, Pradella-Hallinan M, Tufik S, de Mello MT, Mougin F, Dâmaso AR, Thivel D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32861060

Résumé

Pediatric obesity and sleep-disordered breathing (SDB) are strongly associated, and both promote metabolic impairments. However, the effects of a lifestyle intervention on the overall metabolic syndrome (MetS) are unknown. The objectives were i) to evaluate the effects of a lifestyle intervention on cardiometabolic risk (CMR), assessed with a dichotomous (MetS) and a continuous (MetScore) instrument, in obese adolescents with and without SDB and ii) to compare the post-intervention cardiometabolic responses between adolescents with persistent (apnea-hypopnea index; AHI≥2) or normalized-SDB (AHI<2).

Mots clés

Cardiometabolic risk, Chronic exercise, Leptin resistance, Pediatric obesity, Polysomnography, Sleep apnea

Référence

Sleep Med.. 2020 Jun 30;75:225-235