Protocol of DEXPED trial: efficacy of intravenous dexamethasone, administered at the time of analgesic blocking of the lower limb, on postoperative pain in children: a randomised, placebo-controlled, double-blind trial.

Date publication

septembre 2020

Journal

BMJ open

Auteurs

Membres identifiés du Cancéropôle Est :
Pr THILLY Nathalie

Tous les auteurs :
Vautrin N, Thilly N, Bernard Y, Wurtz F, Meistelman C

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/32998920

Résumé

Dexamethasone is a drug used to prolong the postoperative analgesia in children after peripheral nerve blockade, although the dose usually used (0.2 mg/kg) has not been studied yet. This study is a monocentric, prospective, randomised, placebo-controlled, double-blinded study in a university hospital in France. The primary objective of the study is to evaluate the efficacy of 0.2 mg/kg intravenous dexamethasone on early postoperative pain in children aged 6-15 years, who require a lower limb peripheral nerve block following general anaesthesia.

Mots clés

paediatric anaesthesia, paediatric orthopaedic & trauma surgery, paediatric orthopaedics, pain management