A nonradiated grade II glioma that underwent delayed malignant transformation to a gliosarcoma with meningeal growth and dissemination.

Date publication

novembre 2014

Journal

Journal of neurological surgery. Part A, Central European neurosurgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr TAILLANDIER Luc , Pr GAUCHOTTE Guillaume , Dr RECH Fabien

Tous les auteurs :
Rech F, Rigau V, Fabbro M, Kerr C, Gauchotte G, Taillandier L, Duffau H

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/24971682

Résumé

Secondary gliosarcomas are rare tumors, especially those arising from a World Health Organization (WHO) grade II glioma not irradiated. We report a case with subtotal resection for a WHO grade II oligoastrocytoma, without adjuvant treatment, whose metaplastic transformation into gliosarcoma suddenly occurred 4 years later with meningeal dissemination. We show a favorable outcome after therapeutic management of this rare entity.

Mots clés

Astrocytoma, pathology, Brain Neoplasms, drug therapy, Female, Gliosarcoma, pathology, Humans, Meningeal Neoplasms, pathology, Middle Aged, Neoplasm Grading, Neoplasm Recurrence, Local, drug therapy, Treatment Outcome

Référence

J Neurol Surg A Cent Eur Neurosurg. 2014 Nov;75(6):485-90