Central pulse pressure is a determinant of heart and brain remodeling in the elderly: a quantitative MRI and PET pilot study.

Date publication

juillet 2015

Journal

Journal of hypertension

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MARIE Pierre-Yves , Pr VERGER Antoine

Tous les auteurs :
Verger A, van der Gucht A, Guedj E, Marie PY, Hossu G, Mandry D, Morel O, Perrin M, Fay R, Benetos A, Joly L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25827431

Résumé

The sustained elevation of blood pressure (BP) and especially of central pulse pressure (cPP) leads to heart and brain damage. This pilot study was aimed to precise the relationships between peripheral and central BP levels, and the remodeling of heart and brain as objectively quantified by cardiac MRI and brain F-fluorodeoxyglucose (FDG)-PET imaging in the elderly.

Mots clés

Aged, Aged, 80 and over, Blood Pressure, Blood Pressure Determination, Brain, metabolism, Female, Humans, Hypertension, physiopathology, Magnetic Resonance Imaging, Male, Myocardium, metabolism, Pilot Projects, Pulse

Référence

J. Hypertens.. 2015 Jul;33(7):1378-85