Fiche publication


Date publication

janvier 2021

Journal

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NOEL Georges


Tous les auteurs :
Kuntz L, Noel G

Résumé

Stereotactic radiotherapy has become a standard in the management of patients with brain metastases; its main interest is to differ whole brain radiotherapy, provider of neurocognitive toxicity and to increase the rate of local control. The repetition of radiotherapy sessions under stereotactic conditions is not codified, neither on the number of technically and clinically possible sessions, nor on the maximum total number or volume of metastases to be treated. The purpose of this review is to analyse the data in the literature concerning repeated irradiations under stereotactic conditions. The second reirradiation in stereotactic condition shows satisfactory results in terms of overall survival, local control, and toxicity. However, we lack data for patients receiving more than two sessions of SRS as well as to define dose constraints to reirradiated healthy tissues. Prospective trials are still needed to validate the management of recurrent brain metastases after initial SRS.

Mots clés

Brain metastases, Métastases cérébrales, Radiotherapy, Radiothérapie, Radiothérapie en conditions stéréotaxiques, Reirradiation, Repeated radiosurgery, Réirradiation, Stereotactic radiosurgery, Stéréotaxie répétée

Référence

Cancer Radiother. 2021 Jan 8;: