Early liver transplantation for corticosteroid non-responders in acute severe autoimmune hepatitis: the SURFASA score.

Date publication

janvier 2021

Journal

Journal of hepatology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DI MARTINO Vincent

Tous les auteurs :
De Martin E, Coilly A, Chazouillères O, Roux O, Peron JM, Houssel-Debry P, Artru F, Silvain C, Ollivier-Hourmand I, Duvoux C, Heurgue-Berlot A, Barge S, Ganne-Carrié N, Pageaux GP, Besch C, Bourlière M, Fontaine H, de Ledinghen V, Dumortier J, Conti F, Radenne S, Debette-Gratien M, Goria O, Durand F, Potier P, Di Martino V, Reboux N, Ichai P, Sebagh M, Mathurin P, Agostini H, Samuel D, Duclos-Vallée JC,

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/33503489

Résumé

In acute severe autoimmune hepatitis (AS-AIH), the optimal timing for liver transplantation (LT) remains controversial. The objectives of this study were to determine early predictive factors for a non-response to corticosteroids and to propose a score to identify patients in whom LT is urgently indicated.

Mots clés

autoimmune hepatitis, corticosteroid therapy, liver transplantation, prognostic score, severe acute hepatitis

Référence

J Hepatol. 2021 Jan 24;: