Fiche publication


Date publication

février 2021

Journal

Cardiovascular research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GAUCHOTTE Guillaume


Tous les auteurs :
Lagrange J, Worou ME, Michel JB, Raoul A, Didelot M, Muczynski V, Legendre P, Plénat F, Gauchotte G, Lourenco-Rodrigues MD, Christophe OD, Lenting PJ, Lacolley P, Denis CV, Regnault V

Résumé

Von Willebrand factor (VWF) is a plasma glycoprotein involved in primary hemostasis, while also having additional roles beyond hemostasis namely in cancer, inflammation, angiogenesis and potentially in vascular smooth muscle cell (VSMC) proliferation. Here, we addressed how VWF modulates VSMC proliferation and investigated the underlying molecular pathways and the in vivo pathophysiological relevance.

Référence

Cardiovasc Res. 2021 Feb 12;: