Fiche publication


Date publication

février 2020

Journal

Transplantation

Auteurs

Membres identifiés du Cancéropôle Est :
Dr VILLA Pascal


Tous les auteurs :
Nemska S, Daubeuf F, Obrecht A, Israel-Biet D, Stern M, Kessler R, Roux A, Tavakoli R, Villa P, Tissot A, Danger R, Reber L, Durand E, Foureau A, Brouard S, Magnan A, Frossard N,

Résumé

Chronic lung allograft dysfunction (CLAD) and its obstructive form, the obliterative bronchiolitis (OB), are the main long-term complications related to high mortality rate post-lung transplantation. CLAD treatment lacks a significant success in survival. Here, we investigated a new strategy through inhibition of the pro-inflammatory Mitogen and Stress Activated Kinase 1 (MSK1) kinase.

Référence

Transplantation. 2020 Feb 3;: