Stress-first protocol for myocardial perfusion SPECT imaging with semiconductor cameras: high diagnostic performances with significant reduction in patient radiation doses.

Date publication

juin 2015

Journal

European journal of nuclear medicine and molecular imaging

Auteurs

Membres identifiés du Cancéropôle Est :
Pr KARCHER Gilles , Pr MARIE Pierre-Yves , Pr VERGER Antoine , Dr CLAUDIN Marine

Tous les auteurs :
Perrin M, Djaballah W, Moulin F, Claudin M, Veran N, Imbert L, Poussier S, Morel O, Besseau C, Verger A, Boutley H, Karcher G, Marie PY

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25711177

Résumé

Effective doses of 14 mSv or higher are currently being attained in patients having stress and rest myocardial perfusion imaging (MPI) single photon emission computed tomography (SPECT) performed on the same day with conventional protocols. This study aimed to assess the actual reduction in effective doses as well as diagnostic performances for MPI routinely planned with: (1) high-sensitivity cadmium zinc telluride (CZT) cameras, (2) very low injected activities and (3) a stress-first protocol where the normality of stress images may lead to avoiding rest imaging.

Mots clés

Aged, Cadmium, Coronary Angiography, instrumentation, Exercise Test, methods, Female, Humans, Male, Middle Aged, Myocardial Perfusion Imaging, instrumentation, Radiation Dosage, Radiopharmaceuticals, adverse effects, Semiconductors, Technetium Tc 99m Sestamibi, adverse effects, Tellurium, Tomography, Emission-Computed, Single-Photon, instrumentation, Zinc

Référence

Eur. J. Nucl. Med. Mol. Imaging. 2015 Jun;42(7):1004-11