Fiche publication


Date publication

avril 2021

Journal

Clinical and translational gastroenterology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DI MARTINO Vincent , Mme LAHEURTE Caroline


Tous les auteurs :
Weil D, Di Martino V, Mourey G, Biichle S, Renaudin A, Laheurte C, Cypriani B, Delabrousse E, Grandclément E, Thévenot T, Saas P,

Résumé

Microvesicles (MVs) with procoagulant properties may favor liver parenchymal extinction, then cirrhosis-related complications and mortality. In a longitudinal cohort of cirrhotic patients, we measured plasma levels of platelet-derived MVs (PMVs), endothelial-derived MVs, and red blood cell-derived MVs, expressing phosphatidylserine (annexin V-positive [AV+]) or not, and evaluated their impact on Model for End-Stage Liver Disease (MELD) score and transplant-free survival.

Référence

Clin Transl Gastroenterol. 2021 Apr 28;12(5):e00333