Breast cancer patients treated with intrathecal therapy for leptomeningeal metastases in a large real-life database.

Fiche publication

Date publication

mai 2021

Journal

ESMO open

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PETIT Thierry , Dr FUMET Jean-David , Dr JOUANNAUD Christelle

Tous les auteurs :
Carausu M, Carton M, Darlix A, Pasquier D, Leheurteur M, Debled M, Mouret-Reynier MA, Goncalves A, Dalenc F, Verret B, Campone M, Augereau P, Ferrero JM, Levy C, Fumet JD, Lefeuvre-Plesse C, Petit T, Uwer L, Jouannaud C, Larrouquere L, Chevrot M, Courtinard C, Cabel L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/33984675

Résumé

Leptomeningeal metastasis (LM) is a rare complication of metastatic breast cancer (MBC), with high morbidity/mortality rates. Our study aimed to describe the largest-to-date real-life population of MBC patients treated with intrathecal (IT) therapy and to evaluate prognostic models.