Fiche publication


Date publication

mai 2021

Journal

The Journal of allergy and clinical immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr LIPSKER Dan


Tous les auteurs :
Groß M, Speckmann C, May A, Gajardo-Carrasco T, Wustrau K, Maier SL, Panning M, Huzly D, Agaimy A, Bryceson YT, Choo S, Chow CW, Dückers G, Fasth A, Fraitag S, Gräwe K, Haxelmans S, Holzinger D, Hudowenz O, Hübschen J, Khurana C, Kienle K, Klifa R, Korn K, Kutzner H, Lämmermann T, Ledig S, Lipsker D, Meeths M, Naumann-Bartsch N, Rascon J, Schänzer A, Seidl M, Tesi B, Vauloup-Fellous C, Vollmer-Kary B, Warnatz K, Wehr C, Neven B, Vargas P, Sepulveda FE, Lehmberg K, Schmitt-Gräff A, Ehl S

Résumé

Rubella virus-induced granulomas have been described in patients with various inborn errors of immunity. Most defects impair T-cell immunity, suggesting a critical role of T cells in rubella elimination. However, the molecular mechanism of virus control remains elusive.

Mots clés

Cytotoxicity, Griscelli syndrome type 2, granuloma, hemophagocytic lymphohistiocytosis, live vaccine, primary immunodeficiency, rubella virus

Référence

J Allergy Clin Immunol. 2021 May 22;: