Fiche publication


Date publication

avril 2021

Journal

Cancers

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GHIRINGHELLI François , Mme TRUNTZER Caroline


Tous les auteurs :
Lecuelle J, Aarnink A, Tharin Z, Truntzer C, Ghiringhelli F

Résumé

The first line treatment of advanced pancreatic ductal adenocarcinoma cancer (PDAC) comprises a FOLFIRINOX regimen for most patients with good performance status. However, no biomarker to predict efficacy is currently available. We investigated whether exome sequencing could be used to predict progression-free and overall survival in patients undergoing FOLFIRINOX for PDAC.

Mots clés

FOLFIRINOX exome sequencing, PDAC, prognostic biomarkers

Référence

Cancers (Basel). 2021 Apr 13;13(8):