Fiche publication


Date publication

mai 2021

Journal

European journal of heart failure

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick


Tous les auteurs :
Ferreira JP, Konstam MA, McMurray JJV, Butler J, Girerd N, Rossignol P, Sharma A, Voors AA, Lam CSP, Packer M, Zannad F

Résumé

In heart failure with reduced ejection fraction (HFrEF), guidelines recommend up-titration of angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptors blockers (ARBs) to the maximum tolerated dose. However, some studies suggest that women might need lower doses of ACEi/ARBs than men to achieve similar treatment benefit.

Mots clés

dose-response, heart failure, machine learning, sex differences, treatment dose

Référence

Eur J Heart Fail. 2021 May 29;: