Fiche publication


Date publication

mai 2021

Journal

Biomolecules

Auteurs

Membres identifiés du Cancéropôle Est :
Dr HERVOUET Eric , Dr PEIXOTO Paul


Tous les auteurs :
Lachat C, Peixoto P, Hervouet E

Résumé

Epithelial to mesenchymal transition (EMT) is a process that allows epithelial cells to progressively acquire a reversible mesenchymal phenotype. Here, we recount the main events in the history of EMT. EMT was first studied during embryonic development. Nowadays, it is an important field in cancer research, studied all around the world by more and more scientists, because it was shown that EMT is involved in cancer aggressiveness in many different ways. The main features of EMT's involvement in embryonic development, fibrosis and cancers are briefly reviewed here.

Mots clés

EMT, cancer, development

Référence

Biomolecules. 2021 May 22;11(6):