Fiche publication
Date publication
juin 2021
Journal
Journal for immunotherapy of cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GHIRINGHELLI François
,
Mme TRUNTZER Caroline
,
Dr VEGRAN Frédérique
,
Dr REBE Cédric
,
Dr CHALMIN Fanny
,
Dr DERANGERE Valentin
,
Dr THIBAUDIN Marion
Tous les auteurs :
Niogret J, Berger H, Rebe C, Mary R, Ballot E, Truntzer C, Thibaudin M, Derangère V, Hibos C, Hampe L, Rageot D, Accogli T, Joubert P, Routy B, Harker J, Vegran F, Ghiringhelli F, Chalmin F
Lien Pubmed
Résumé
T follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in various human cancers, with positive or negative prognostic roles. However, the mechanisms explaining the accumulation of Tfh and their role in cancer remain obscure.
Mots clés
CD8-positive T-lymphocytes, immunotherapy, programmed cell death 1 receptor
Référence
J Immunother Cancer. 2021 Jun;9(6):
