Fiche publication
Date publication
mai 2015
Journal
FEMS microbiology reviews
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ROMBY Pascale
Tous les auteurs :
Durand S, Tomasini A, Braun F, Condon C, Romby P
Lien Pubmed
Résumé
It is widely recognized that RNA degradation plays a critical role in gene regulation when fast adaptation of cell growth is required to respond to stress and changing environmental conditions. Bacterial ribonucleases acting alone or in concert with various trans-acting regulatory factors are important mediators of RNA degradation. Here, we will give an overview of what is known about ribonucleases in several Gram-positive bacteria, their specificities and mechanisms of action. In addition, we will illustrate how sRNAs act in a coordinated manner with ribonucleases to regulate the turnover of particular mRNA targets, and the complex interplay existing between the ribosome, the ribonucleases and RNAs.
Mots clés
Gram-Positive Bacteria, genetics, RNA, Bacterial, metabolism, RNA, Messenger, metabolism, Ribonucleases, metabolism, Ribosomes, metabolism, Stress, Physiological, genetics
Référence
FEMS Microbiol. Rev.. 2015 May;39(3):316-30
