Fiche publication
Date publication
septembre 2021
Journal
Journal of biomedical materials research. Part B, Applied biomaterials
Auteurs
Membres identifiés du Cancéropôle Est :
Pr AUBER Frédéric
,
Pr HOCQUET Didier
Tous les auteurs :
Roina Y, Auber F, Hocquet D, Herlem G
Lien Pubmed
Résumé
Polytetrafluoroethylene (PTFE) is a ubiquitous material used for implants and medical devices in general because of its high biocompatibility and inertness: blood vessel, heart, table jawbone, nose, eyes, or abdominal wall can benefit from its properties in case of disease or injury. Its expanded version, ePTFE is an improved version of PTFE with better mechanical properties, which extends its medical applications. A material as frequently used as ePTFE with these exceptional properties deserves a review of its main uses, developments, and possibility of improvements. In this systematic review, we examined clinical trials related to ePTFE-based medical devices from the literature. Then, we excluded all trials using ePTFE as a control to test other devices. ePTFE-coated stents, hemodialysis and bypass grafts, guided bone and tissue regeneration membranes, hernia and heart repair and other devices are reviewed. The rates of success using these devices and their efficiency compared to other materials used for the same purposes are reported. ePTFE appears to be more or just as efficient compared to them. Some success rates remain low, suggesting the need of improvement ePTFE for medical applications.
Mots clés
clinical trials, ePTFE, implant, membrane barrier, stent, vascular graft
Référence
J Biomed Mater Res B Appl Biomater. 2021 Sep 14;: