Innovative procedure for measuring left ventricular ejection fraction from F-FDG first-pass ultra-sensitive digital PET/CT images: evaluation with an anthropomorphic heart phantom.

Fiche publication

Date publication

mai 2021

Journal

EJNMMI physics

Auteurs

Membres identifiés du Cancéropôle Est :
Dr RETIF Paul

Tous les auteurs :
Verrecchia-Ramos E, Morel O, Retif P, Ben Mahmoud S

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/34018067

Résumé

Left ventricular ejection fraction (LVEF) is usually measured by cine-cardiac magnetic resonance imaging (MRI), planar and single-photon emission-computerized tomography (SPECT) equilibrium radionuclide angiocardiography (ERNA), and echocardiography. It would be clinically useful to measure LVEF from first-pass positron-emission tomography/computed tomography (PET/CT) radionuclide angiography, but this approach has been limited by fast radiotracer diffusion. Ultra-sensitive digital PET systems can produce high-quality images within 3-s acquisition times. This study determined whether digital PET/CT accurately measured LVEF in an anthropomorphic heart phantom under conditions mimicking radiotracer first-pass into the cardiac cavities.