Septic shock as a trigger of arterial stress-induced premature senescence: A new pathway involved in the post sepsis long-term cardiovascular complications.

Fiche publication

Date publication

septembre 2021

Journal

Vascular pharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SCHINI-KERTH Valérie , Dr AUGER Cyril

Tous les auteurs :
Merdji H, Kassem M, Chomel L, Clere-Jehl R, Helms J, Kurihara K, Chaker AB, Auger C, Schini-Kerth V, Toti F, Meziani F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/34592427

Résumé

Major adverse cardiovascular events among sepsis survivors is an emerging health issue. Because endothelial senescence leads to vascular dysfunction and atherothrombosis, sepsis could be associated to vascular stress-induced premature senescence and thus with long-term cardiovascular events.