Fiche publication


Date publication

octobre 2021

Journal

British journal of clinical pharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CHASTAGNER Pascal , Pr ENTZ-WERLE Natacha


Tous les auteurs :
Hamimed M, Gattacceca F, André N, Tresch-Bruneel E, Probst A, Chastagner P, Pagnier A, De Carli E, Entz-Werlé N, Grill J, Aerts I, Frappaz D, Bertozzi-Salamon AI, Solas C, Leblond P

Résumé

There is a crucial need for pharmacokinetic (PK) data of oral vinorelbine (VNR) in pediatric population. The aim of this work was to assess the PK profile of orally administered VNR in children with recurrent/progressive primary low-grade glioma (LGG).

Mots clés

Low-grade glioma, between subject variability, exposure matching, non-compartmental analysis, pediatrics, pharmacokinetics, vinorelbine

Référence

Br J Clin Pharmacol. 2021 Oct 28;: