Correlation Between Microvascular Inflammation in Endomyocardial Biopsies and Rejection Transcripts, Donor-specific Antibodies, and Graft Dysfunction in Antibody-mediated Rejection.

Date publication

décembre 2021

Journal

Transplantation

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CHENARD Marie-Pierre

Tous les auteurs :
Coutance G, Zouhry I, Racapé M, Drieux F, Viailly PJ, Rouvier P, François A, Chenard MP, Toquet C, Rabant M, Berry GJ, Angelini A, Bruneval P, Duong Van Huyen JP

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/34954735

Résumé

The pathology-based diagnosis of cardiac antibody-mediated rejection (AMR) relies on the 2013 International Society for Heart and Lung Transplantation Working Formulation, in which microvascular inflammation (MVI) is considered as present or absent regardless of its extent. This work assessed the biological and clinical value of a semiquantitative evaluation of the extent of MVI in endomyocardial biopsies (EMBs).

Référence

Transplantation. 2021 Dec 21;: