Fiche publication


Date publication

janvier 2021

Journal

PeerJ

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BAHRAM Siamak


Tous les auteurs :
Zaloszyc A, Schmitt CP, Sayeh A, Higel L, Gros CI, Bornert F, Aubertin-Kirch G, Dillenseger JP, Goetz C, Constantinesco A, Fischbach M, Bahram S, Choquet P

Résumé

To provide insight into bone turnover, quantitative measurements of bone remodeling are required. Radionuclide studies are widely used in clinical care, but have been rarely used in the exploration of the bone in preclinical studies. We describe a bone planar scintigraphy method for frequent assessment of bone activity in mice across the growing period. Since repeated venous radiotracer injections are hardly feasible in mice, we investigated the subcutaneous route.

Mots clés

Growth, Mice, Radionuclide imaging, Subcutaneous application

Référence

PeerJ. 2021 ;9:e12355