Fiche publication
Date publication
janvier 2022
Journal
Journal of ovarian research
Auteurs
Membres identifiés du Cancéropôle Est :
Dr AMIOT Clotilde
,
Pr GARNACHE-OTTOU Francine
,
Dr KOSCINSKI Isabelle
,
Pr ROUX Christophe
Tous les auteurs :
Zver T, Frontczak S, Poirot C, Rives-Feraille A, Leroy-Martin B, Koscinski I, Arbez-Gindre F, Garnache-Ottou F, Roux C, Amiot C
Lien Pubmed
Résumé
Cryopreservation of ovarian tissue is a fertility-preservation option for women before gonadotoxic treatments. However, cryopreserved ovarian tissue transplantation must be performed with caution in women with malignancies that may metastasize to the ovaries. For this purpose, detecting minimal residual disease (MRD) in the ovarian cortex using sensitive methods is a crucial step. We developed an automated ovarian tissue dissociation method to obtain ovarian cell suspensions.
Mots clés
Fertility preservation, Minimal residual disease, Multicolor flow cytometry, Ovarian tissue cryopreservation
Référence
J Ovarian Res. 2022 Jan 18;15(1):9
