Impact of repeated measures of joint space width on the sample size calculation: An application to hip osteoarthritis.

Date publication

mai 2015

Journal

Joint bone spine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ORNETTI Paul

Tous les auteurs :
Ornetti P, Gossec L, Laroche D, Combescure C, Dougados M, Maillefert JF

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25575611

Résumé

The aims of the study were to investigate the impact of aggregation of repeated readings (a) on minimising variability of joint space width (JSW) measurements based on calculation of the smallest detectable difference (SDD) and (b) on sample size calculation in a hip OA randomized controlled trial (RCT).

Mots clés

Hip, Joint space, Osteoarthritis, Randomized clinical trial, Sample size, Smallest detectable difference

Référence

Joint Bone Spine. 2015 May;82(3):172-6