Increased cardiac uptake of (18F)-fluorodeoxyglucose incidentally detected on positron emission tomography after left breast irradiation: How to interpret?

Date publication

février 2022

Journal

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ANTONI Delphine , Pr NOEL Georges , Dr EBER Jordan

Tous les auteurs :
Eber J, Leroy-Freschini B, Antoni D, Noël G, Pflumio C

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/35165015

Résumé

Radiation-induced heart disease is a complication that occurs years after thoracic irradiation. Recent studies suggest that radiation-induced heart disease could be an earlier complication and that subclinical cardiac injury can be detected. The present case described an increased uptake of (18F)-fluorodeoxyglucose incidentally detected on positron emission tomography after left breast irradiation with slightly reversible perfusion defect on (99mTc)-tetrofosmin single photon emission computed tomography. The cardiac clinical examination was asymptomatic, and the patient had a normal angiography, suggesting a radiation-induced hibernating myocardium. The relevant question is: how far should an incidentally (18F)-fluorodeoxyglucose uptake be explored?

Mots clés

(18F)-fluorodeoxyglucose positron emission tomography, Breast cancer, Cancer du sein, Cœur, Heart, Radiation toxicity, Radiotherapy, Radiothérapie, Tomographie par émission de positrons au (18F)-fluorodésoxyglucose, Toxicité radio-induite

Référence

Cancer Radiother. 2022 Feb 11;: