Association of cerebral microbleeds with cerebrospinal fluid Alzheimer-biomarkers and clinical symptoms in early dementia with Lewy bodies.

Date publication

juin 2021

Journal

International journal of geriatric psychiatry

Auteurs

Membres identifiés du Cancéropôle Est :
Dr NOBLET Vincent

Tous les auteurs :
Mendes A, Noblet V, Mondino M, Loureiro de Sousa P, Manji S, Archenault A, Casanovas M, Bousiges O, Philippi N, Baloglu S, Rauch L, Cretin B, Demuynck C, Martin-Hunyadi C, Blanc F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/33300151

Résumé

To determine the prevalence, localization and associations of cerebral microbleeds (CMB) in dementia with Lewy bodies (DLB) with its core clinical symptoms and cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD). We hypothesize DLB patients with CMB have increased amyloid burden compared to those without CMB, which could also translate into clinical differences.

Mots clés

Alzheimer's disease, CSF biomarkers, Lewy-bodies dementia, cerebral amyloid angiopathy, cerebral microbleeds

Référence

Int J Geriatr Psychiatry. 2021 06;36(6):851-857