[Tridimensional in vitro models of nervous and immune systems in the skin].

Date publication

janvier 2021

Journal

Medecine sciences : M/S

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FLACHER Vincent

Tous les auteurs :
Muller Q, Berthod F, Flacher V

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/33492221

Résumé

The immune system and the sensory nervous system are responsible for perceiving danger under distinct yet complementary forms. In the last few years, neuroimmune interactions have become an important topic of dermatological research for conditions including wound healing, atopic dermatitis and psoriasis. We present here a selection of tridimensional in vitro models that reproduce skin structure and integrate an immune or a sensory function. Future evolutions of such models are expected to greatly contribute in a better understanding of reciprocal influences between sensory nervous system and immune system.

Mots clés

Animals, Cells, Cultured, Humans, Models, Biological, Neuroimmunomodulation, physiology, Organ Culture Techniques, Skin, immunology, Tissue Culture Techniques, methods, Tissue Engineering, methods, Tissue Scaffolds, Wound Healing, physiology

Référence

Med Sci (Paris). 2021 Jan;37(1):68-76