Fiche publication
Date publication
juillet 2020
Journal
Alzheimer's research & therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr NOBLET Vincent
Tous les auteurs :
Philippi N, Noblet V, Hamdaoui M, Soulier D, Botzung A, Ehrhard E, Cretin B, Blanc F,
Lien Pubmed
Résumé
Despite the growing number of discoveries during the past decades about its functions, the insula remains a mysterious 'island'. In addition to its involvement in basic functions such as gustation and interoception, the insular cortex is now considered a key region for integrated functions such as emotion/motivation processing, decision-making and self-consciousness. We hypothesized that this structure, standing at the crossroads of such functions, could ground personal tastes in general, beyond food preferences and aesthetic judgements. Given that dementia with Lewy bodies is characterized by a focal atrophy within the insular cortex from the early stages, this condition provides an opportunity to test such a hypothesis.
Mots clés
Dementia with Lewy bodies, Insula, Personal preferences, Personal tastes, Self
Référence
Alzheimers Res Ther. 2020 07 6;12(1):79
