Fiche publication
Date publication
janvier 2020
Journal
Parasite (Paris, France)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VILLENA Isabelle
Tous les auteurs :
Simon L, Fillaux J, Guigon A, Lavergne RA, Villard O, Villena I, Marty P, Pomares C,
Lien Pubmed
Résumé
Primary infection by Toxoplasma gondii in pregnant women can result in serious outcomes for the foetus. A false-positive IgG result during pregnancy can lead to a misdiagnosis of past infection and to stopping preventive measures. We collected 189 sera with positive Architect Toxo IgG assay (Abbott Laboratories) and negative IgG results with at least two other serological tests, in order to find an explanation for the suspected false-positive IgG results. We used the recomLine Toxoplasma IgG immunoblot (Mikrogen Diagnostik) to search for specific antigenic reactivities of the sera, and the LDBio Toxo II IgG immunoblot (LDBio Diagnostics) as a confirmatory test.
Mots clés
Architect, False-positive, IgG, Serology, Toxoplasma gondii, Toxoplasmosis
Référence
Parasite. 2020 ;27:7
