Pay attention to the basal ganglia: a volumetric study in early dementia with Lewy bodies.

Date publication

décembre 2019

Journal

Alzheimer's research & therapy

Auteurs

Membres identifiés du Cancéropôle Est :
Dr NOBLET Vincent

Tous les auteurs :
Botzung A, Philippi N, Noblet V, Loureiro de Sousa P, Blanc F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/31864422

Résumé

Cortical and subcortical cognitive impairments are usually found in dementia with Lewy bodies (DLB). Roughly, they comprise visuo-constructive/executive function and attention/processing speed impairments, whereas memory would remain relatively spared. In this study, we focused on the neuro-anatomical substrates of attention and processing speed, which is still poorly understood. For the purpose of the study, we examined the correlations between behavioral scores measuring the speed of processing and the degree of cerebral atrophy in patients with prodromal to moderate DLB.

Mots clés

Attention, Basal ganglia, Dementia with Lewy bodies, MRI, Mild cognitive impairment, Neuroimaging, Processing speed, Prodromal, VBM

Référence

Alzheimers Res Ther. 2019 12 21;11(1):108