Xylanase production by Thermobacillus xylanilyticus is impaired by population diversification but can be mitigated based on the management of cheating behavior.

Date publication

mars 2022

Journal

Microbial cell factories

Auteurs

Membres identifiés du Cancéropôle Est :
Dr VELARD Frédéric , Dr AUDONNET Sandra

Tous les auteurs :
Bouchat R, Vélard F, Audonnet S, Rioult D, Delvigne F, Rémond C, Rakotoarivonina H

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/35292016

Résumé

The microbial production of hemicellulasic cocktails is still a challenge for the biorefineries sector and agro-waste valorization. In this work, the production of hemicellulolytic enzymes by Thermobacillus xylanilyticus has been considered. This microorganism is of interest since it is able to produce an original set of thermostable hemicellulolytic enzymes, notably a xylanase GH11, Tx-xyn11. However, cell-to-cell heterogeneity impairs the production capability of the whole microbial population.

Mots clés

Cell sorting, Hemicellulases, Population diversification, Substrate switch, Successive cultivation, Thermobacillus xylanilyticus, Xylanases

Référence

Microb Cell Fact. 2022 Mar 15;21(1):39