Healing of diabetic foot ulcers is independently associated with the use of angiotensin receptor blockers but not with those of diuretics and angiotensin conversion enzyme inhibitors.

Date publication

mars 2022

Journal

Diabetes & metabolism

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PETIT Jean-Michel , Pr VERGES Bruno

Tous les auteurs :
Lapray M, Petit JM, Fourmont C, Rouland A, Vergès B, Bouillet B

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/35245656

Résumé

Dysregulation of the renin angiotensin system (RAS) has been proven in diabetic animal models, and studies in humans show that diuretic use is associated with lower limb amputation in diabetes. While patients with diabetes are often treated with diuretics and RAS blockers, the association between wound healing and these treatments is still unknown. We aimed to determine whether the use of diuretics and RAS blockers could influence healing of diabetic foot ulcers (DFU).

Mots clés

Angiotensin conversion enzyme inhibitors, Angiotensin receptor blockers, Diabetes mellitus, Diabetic foot ulcer, Diuretics, Healing

Référence

Diabetes Metab. 2022 Mar 1;:101336