Fiche publication
Date publication
avril 2022
Journal
BMC cardiovascular disorders
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ZANETTA Sylvie
Tous les auteurs :
Hamdan R, Petit V, Zanetta S, Eicher JC, Mourot M
Lien Pubmed
Résumé
High-output heart failure is a rare condition that occurs when the heart is unable to respond to a sustained increase in blood demand. On echocardiography, a cardiac index of > 4 L/min/m (or 6 L/min) is a clear indicator of this disorder. The causes of high-output heart failure vary, but they all involve peripheral vasodilation or arteriovenous shunting. Renal cell carcinoma is well known for producing high levels of angiogenic growth factors that induce arteriovenous shunts. The decrease in peripheral arterial resistance and the increase in venous return result in a permanent high cardiac output, followed by congestive heart failure. Single bone metastases of renal clear cell carcinoma tumours causing high cardiac output and heart failure symptoms have been reported less than ten times in the medical literature.
Mots clés
Arteriovenous shunts, Case report, Doppler ultrasound, Hemodynamic, High-output heart failure, Metastatic renal cell carcinoma
Référence
BMC Cardiovasc Disord. 2022 Apr 5;22(1):149
