Fiche publication


Date publication

mai 2022

Journal

EJNMMI physics

Auteurs

Membres identifiés du Cancéropôle Est :
Pr IMPERIALE Alessio , Dr POROT Clémence


Tous les auteurs :
Mazzara C, Salvadori J, Ritzenthaler F, Martin S, Porot C, Imperiale A

Résumé

Given the recent and rapid development of peptide receptor radionuclide therapy (PRRT), increasing emphasis should be placed on the early identification and quantification of therapeutic radiopharmaceutical (thRPM) extravasation during intravenous administration. Herein, we provide an analytical model of Lu-DOTA0-Tyr3-octreotate (Lutathera) infusion for real-time detection and characterization of thRPM extravasation.

Mots clés

177Lu, Equivalent dose rate, Extravasation, Gravity infusion method, Lutathera, Neuroendocrine tumors, Peptide receptor radionuclide therapy, Radioprotection

Référence

EJNMMI Phys. 2022 May 3;9(1):33