Orbital Metastasis: A Rare but Typical Location of Small Intestine Neuroendocrine Tumor on 18F-FDOPA PET/CT.

Date publication

août 2022

Journal

Clinical nuclear medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CADIOT Guillaume , Pr PAPATHANASSIOU Dimitri

Tous les auteurs :
Morland D, Jallet L, Deguelte S, Cadiot G, Papathanassiou D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/35797630

Résumé

Orbital foci of increased uptake are sometimes visualized on 18F-FDOPA PET/CT, but the literature remains poor as to their nature. The orbit is indeed a rare site of metastatic involvement. Given this low probability of metastatic location, the question of an incidental benign finding may arise. We reviewed all 18F-FDOPA PET/CT examinations performed at our institution between January 2015 and May 2021: 4/149 patients presented at least 1 orbital focus of increased uptake, all of them presented a metastatic small intestine neuroendocrine tumor. Somatostatin receptor expression was confirmed using 68Ga-DOTATOC PET/CT supporting the hypothesis of genuine metastases.

Référence

Clin Nucl Med. 2022 08 1;47(8):717-718