Fiche publication


Date publication

juillet 2022

Journal

Journal for immunotherapy of cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BERCEANU Ana , Dr CAILLOT Denis , Pr DECONINCK Eric , Dr FERRAND Christophe , Dr DESCHAMPS Marina , Dr DAGUINDAU Etienne


Tous les auteurs :
Trad R, Warda W, Alcazer V, Neto da Rocha M, Berceanu A, Nicod C, Haderbache R, Roussel X, Desbrosses Y, Daguindau E, Renosi F, Roumier C, Bouquet L, Biichle S, Guiot M, Seffar E, Caillot D, Depil S, Robinet E, Salma Y, Deconinck E, Deschamps M, Ferrand C

Résumé

Acute myeloid leukemia (AML) remains a very difficult disease to cure due to the persistence of leukemic stem cells (LSCs), which are resistant to different lines of chemotherapy and are the basis of refractory/relapsed (R/R) disease in 80% of patients with AML not receiving allogeneic transplantation.

Mots clés

T-lymphocytes, cytotoxicity, immunologic, hematologic neoplasms, immunotherapy

Référence

J Immunother Cancer. 2022 07;10(7):