Carissa edulis Vahl (Apocynaceae) extract, a medicinal plant of Benin pharmacopoeia, induces potent endothelium-dependent relaxation of coronary artery rings involving nitric oxide.

Fiche publication

Date publication

août 2022

Journal

Phytomedicine : international journal of phytotherapy and phytopharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SCHINI-KERTH Valérie , Dr HEINTZ Dimitri , Dr AUGER Cyril

Tous les auteurs :
Hounguè U, Villette C, Tokoudagba JM, Chaker AB, Remila L, Auger C, Heintz D, Gbaguidi FA, Schini-Kerth VB

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/35977457

Résumé

Hypertension is a major cardiovascular risk factor that affects most countries including those of Africa. Although Carissa edulis Vahl, Diodia scandens Sw. and Cleome gynandra L. are traditionally used in Benin as antihypertensive treatments with some efficacy mentioned by the local population, their biological activity on the cardiovascular system remains poorly studied.